Titled “Depression and moyamoya disease”, this fortnight’s Mind Matters column of the Editor-in-Chief of the Open Journal of Psychiatry & Allied Sciences (OJPAS®), Shyamanta Das in Horizon, the Friday supplement with The Assam Tribune highlights the case study, “Diagnostic dilemma of cognitive decline in a young female: considering congenital rubella, depressive disorder, and moyamoya disease” by Robin Victor, Vrinda Saxena, Shailendra Raghuvanshi, and Ravi Gupta, and published in January-June 2020, Volume 11 Issue 1 of OJPAS®.